Diabetes : Symptoms, Causes, Treatment, Prevention


Diabetes mellitus, commonly known as diabetes, is a metabolic disease that causes high blood sugar. The hormone insulin moves sugar from the blood into your cells to be stored or used for energy. With diabetes, your body either doesn’t make enough insulin or can’t effectively use the insulin it does make.
Untreated high blood sugar from diabetes can damage your nerves, eyes, kidneys, and other organs.
There are a few different types of diabetes:
  • Type 1 diabetes is an autoimmune disease. The immune system attacks and destroys cells in the pancreas, where insulin is made. It’s unclear what causes this attack. About 10 percent of people with diabetes have this type.
  • Type 2 diabetes occurs when your body becomes resistant to insulin, and sugar builds up in your blood.
  • Prediabetes occurs when your blood sugar is higher than normal, but it’s not high enough for a diagnosis of type 2 diabetes.
  • Gestational diabetes is high blood sugar during pregnancy. Insulin-blocking hormones produced by the placenta cause this type of diabetes.
A rare condition called diabetes insipidus is not related to diabetes mellitus, although it has a similar name. It’s a different condition in which your kidneys remove too much fluid from your body.
Each type of diabetes has unique symptoms, causes, and treatments. 

Diabetes symptoms are caused by rising blood sugar.

General symptoms

The general symptoms of diabetes include:
  • increased hunger
  • increased thirst
  • weight loss
  • frequent urination
  • blurry vision
  • extreme fatigue
  • sores that don’t heal

Symptoms in men

In addition to the general symptoms of diabetes, men with diabetes may have a decreased sex drive, erectile dysfunction (ED), and poor muscle strength.

Symptoms in women

Women with diabetes can also have symptoms such as urinary tract infections, yeast infections, and dry, itchy skin.

Type 1 diabetes

Symptoms of type 1 diabetes can include:
  • extreme hunger
  • increased thirst
  • unintentional weight loss
  • frequent urination
  • blurry vision
  • tiredness
It may also result in mood changes.

Type 2 diabetes

Symptoms of type 2 diabetes can include:
  • increased hunger
  • increased thirst
  • increased urination
  • blurry vision
  • tiredness
  • sores that are slow to heal
It may also cause recurring infections. This is because elevated glucose levels make it harder for the body to heal.

Gestational diabetes

Most women with gestational diabetes don’t have any symptoms. The condition is often detected during a routine blood sugar test or oral glucose tolerance test that is usually performed between the 24th and 28th weeks of gestation.
In rare cases, a woman with gestational diabetes will also experience increased thirst or urination.

Different causes are associated with each type of diabetes.

Type 1 diabetes

Doctors don’t know exactly what causes type 1 diabetes. For some reason, the immune system mistakenly attacks and destroys insulin-producing beta cells in the pancreas.
Genes may play a role in some people. It’s also possible that a virus sets off the immune system attack.

Type 2 diabetes

Type 2 diabetes stems from a combination of genetics and lifestyle factors. Being overweight or obese increases your risk too. Carrying extra weight, especially in your belly, makes your cells more resistant to the effects of insulin on your blood sugar.
This condition runs in families. Family members share genes that make them more likely to get type 2 diabetes and to be overweight.

Gestational diabetes

Gestational diabetes is the result of hormonal changes during pregnancy. The placenta produces hormones that make a pregnant woman’s cells less sensitive to the effects of insulin. This can cause high blood sugar during pregnancy.
Women who are overweight when they get pregnant or who gain too much weight during their pregnancy are more likely to get gestational diabetes.

Certain factors increase your risk for diabetes.

Type 1 diabetes

You’re more likely to get type 1 diabetes if you’re a child or teenager, you have a parent or sibling with the condition, or you carry certain genes that are linked to the disease.

Type 2 diabetes

Your risk for type 2 diabetes increases if you:
  • are overweight
  • are age 45 or older
  • have a parent or sibling with the condition
  • aren’t physically active
  • have had gestational diabetes
  • have prediabetes
  • have high blood pressure, high cholesterol, or high triglycerides
  • have African American, Hispanic or Latino American, Alaska Native, Pacific Islander, American Indian, or Asian American ancestry

Gestational diabetes

Your risk for gestational diabetes increases if you:
  • are overweight
  • are over age 25
  • had gestational diabetes during a past pregnancy
  • have given birth to a baby weighing more than 9 pounds
  • have a family history of type 2 diabetes
  • have polycystic ovary syndrome (PCOS)

High blood sugar damages organs and tissues throughout your body. The higher your blood sugar is and the longer you live with it, the greater your risk for complications.
Complications associated with diabetes include:
  • heart disease, heart attack, and stroke
  • neuropathy
  • nephropathy
  • retinopathy and vision loss
  • hearing loss
  • foot damage such as infections and sores that don’t heal
  • skin conditions such as bacterial and fungal infections
  • depression
  • dementia

Gestational diabetes

Uncontrolled gestational diabetes can lead to problems that affect both the mother and baby. Complications affecting the baby can include:
  • premature birth
  • higher-than-normal weight at birth
  • increased risk for type 2 diabetes later in life
  • low blood sugar
  • jaundice
  • stillbirth
The mother can develop complications such as high blood pressure (preeclampsia) or type 2 diabetes. She may also require cesarean delivery, commonly referred to as a C-section.
The mother’s risk of gestational diabetes in future pregnancies also increases.

Doctors treat diabetes with a few different medications. Some of these drugs are taken by mouth, while others are available as injections.

Type 1 diabetes

Insulin is the main treatment for type 1 diabetes. It replaces the hormone your body isn’t able to produce.
There are four types of insulin that are most commonly used. They’re differentiated by how quickly they start to work, and how long their effects last:
  • Rapid-acting insulin starts to work within 15 minutes and its effects last for 3 to 4 hours.
  • Short-acting insulin starts to work within 30 minutes and lasts 6 to 8 hours.
  • Intermediate-acting insulin starts to work within 1 to 2 hours and lasts 12 to 18 hours.
  • Long-acting insulin starts to work a few hours after injection and lasts 24 hours or longer.

Type 2 diabetes

Diet and exercise can help some people manage type 2 diabetes. If lifestyle changes aren’t enough to lower your blood sugar, you’ll need to take medication.
These drugs lower your blood sugar in a variety of ways:
Types of drugHow they workExample(s)
Alpha-glucosidase inhibitorsSlow your body’s breakdown of sugars and starchy foodsAcarbose (Precose) and miglitol (Glyset)
BiguanidesReduce the amount of glucose your liver makesMetformin (Glucophage)
DPP-4 inhibitorsImprove your blood sugar without making it drop too lowLinagliptin (Tradjenta), saxagliptin (Onglyza), and sitagliptin (Januvia)
Glucagon-like peptidesChange the way your body produces insulinDulaglutide (Trulicity), exenatide (Byetta), and liraglutide (Victoza)
MeglitinidesStimulate your pancreas to release more insulinNateglinide (Starlix) and repaglinide (Prandin)
SGLT2 inhibitorsRelease more glucose into the urineCanagliflozin (Invokana) and dapagliflozin (Farxiga)
SulfonylureasStimulate your pancreas to release more insulinGlyburide (DiaBeta, Glynase), glipizide (Glucotrol), and glimepiride (Amaryl)
ThiazolidinedionesHelp insulin work betterPioglitazone (Actos) and rosiglitazone (Avandia)
You may need to take more than one of these drugs. Some people with type 2 diabetes also take insulin.

Gestational diabetes

You’ll need to monitor your blood sugar level several times a day during pregnancy. If it’s high, dietary changes and exercise may or may not be enough to bring it down.
According to the Mayo Clinic, about 10 to 20 percent of women with gestational diabetes will need insulin to lower their blood sugar. Insulin is safe for the growing baby.

Healthy eating is a central part of managing diabetes. In some cases, changing your diet may be enough to control the disease.

Type 1 diabetes

Your blood sugar level rises or falls based on the types of foods you eat. Starchy or sugary foods make blood sugar levels rise rapidly. Protein and fat cause more gradual increases.
Your medical team may recommend that you limit the amount of carbohydrates you eat each day. You’ll also need to balance your carb intake with your insulin doses.
Work with a dietitian who can help you design a diabetes meal plan. Getting the right balance of protein, fat, and carbs can help you control your blood sugar.

Type 2 diabetes

Eating the right types of foods can both control your blood sugar and help you lose any excess weight.
Carb counting is an important part of eating for type 2 diabetes. A dietitian can help you figure out how many grams of carbohydrates to eat at each meal.
In order to keep your blood sugar levels steady, try to eat small meals throughout the day. Emphasize healthy foods such as:
  • fruits
  • vegetables
  • whole grains
  • lean protein such as poultry and fish
  • healthy fats such as olive oil and nuts
Certain other foods can undermine efforts to keep your blood sugar in control.

Gestational diabetes

Eating a well-balanced diet is important for both you and your baby during these nine months. Making the right food choices can also help you avoid diabetes medications.
Watch your portion sizes, and limit sugary or salty foods. Although you need some sugar to feed your growing baby, you should avoid eating too much.
Consider making an eating plan with the help of a dietitian or nutritionist. They’ll ensure that your diet has the right mix of macronutrients. 

Women who’ve never had diabetes can suddenly develop gestational diabetes in pregnancy. Hormones produced by the placenta can make your body more resistant to the effects of insulin.
Some women who had diabetes before they conceived carry it with them into pregnancy. This is called pre-gestational diabetes.
Gestational diabetes should go away after you deliver, but it does significantly increase your risk for getting diabetes later.
About half of women with gestational diabetes will develop type 2 diabetes within 5 to 10 years of delivery, according to the International Diabetes Federation (IDF).
Having diabetes during your pregnancy can also lead to complications for your newborn, such as jaundice or breathing problems.
If you’re diagnosed with pre-gestational or gestational diabetes, you’ll need special monitoring to prevent complications.

Children can get both type 1 and type 2 diabetes. Controlling blood sugar is especially important in young people, because the disease can damage important organs such as the heart and kidneys.

Type 1 diabetes

The autoimmune form of diabetes often starts in childhood. One of the main symptoms is increased urination. Kids with type 1 diabetes may start wetting the bed after they’ve been toilet trained.
Extreme thirst, fatigue, and hunger are also signs of the condition. It’s important that children with type 1 diabetes get treated right away. The disease can cause high blood sugar and dehydration, which can be medical emergencies.

Type 2 diabetes

Type 1 diabetes used to be called “juvenile diabetes” because type 2 was so rare in children. Now that more children are overweight or obese, type 2 diabetes is becoming more common in this age group.
About 40 percent of children with type 2 diabetes don’t have symptoms, according to the Mayo Clinic. The disease is often diagnosed during a physical exam.
Untreated type 2 diabetes can cause lifelong complications, including heart disease, kidney disease, and blindness. Healthy eating and exercise can help your child manage their blood sugar and prevent these problems.
Type 2 diabetes is more prevalent than ever in young people. 

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